University of Manchester technology that boosts the understanding of senescent cells role in age-related disorders licensed to Arriani Pharmaceuticals

An exclusive licence deal has been transacted by The University of Manchester’s technology transfer company (UMI3 Ltd) with Arriani Pharmaceuticals for a research tool which boosts the understanding of senescent cells role in diverse age-related diseases including cancer. 

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New method to detect ageing cells – and aid rejuvenation therapies - developed by researchers

Scientists have discovered a new way to look for ageing cells across a wide range of biological materials; the new method will boost understanding of cellular development and ageing as well as the causes of diverse diseases.

For more information, click here.

 

ITN-PhD position on new approaches to target breast and ovarian cancer in the Gorgoulis Group, National Kapodistrian University of Athens

One PhD position is open in the Molecular Carcinogenesis Group headed by Prof Vassilis G Gorgoulis at the Dept of Histology-Embryology, Medical School, National Kapodistrian University of Athens (NKUA), for a highly motivated researcher with a desire to unravel new mechanisms that facilitate breast and ovarian cancer development. The position is part of a newly established European training network, SYNTRAIN.

Read more: ITN-PhD position on new approaches to target breast and ovarian cancer in the Gorgoulis Group,...

The dark side of p21

Prolonged expression of p21 in p53-null cells triggers replication stress.

Read more: The dark side of p21

Highly cited Greek Scientists

Prof Vassilis G Gorgoulis is one of the most highly cited Greek Scientists at international level, also with strong influence on the international scientific literature.

Read more: Highly cited Greek Scientists

Good indicator of cancer prognosis turned on its head by new research

A molecule which, for the last 20 years has been believed to be an indicator of good prognosis in tumours has been shown to have a dark side by new research from The Universities of Manchester, Athens and collaborators, recently published in Nature Cell Biology.

Read more: Good indicator of cancer prognosis turned on its head by new research

IKY-Simens Excellence (Aristeia) 2016 grant application

Ms Eirini-Stavroula Komseli and the Lab of Histology-Embryology, Medical School of Athens, directed by Professor Vassilis G Gorgoulis received an IKY-Siemens Excellence (Aristeia) 2016 grant with the highest evaluation score (100%).

EMBO announces new members for 2015

Heidelberg, 20 May 2015 – EMBO today announced that 58 outstanding researchers in the life sciences were elected to its membership. Fifty of the scientists reside in Europe and neighbouring countries; eight Associate Members were elected from China, Japan, New Zealand and the United States.

Read more: EMBO announces new members for 2015

Typhoid toxin aids survival in mice

A DNA-damaging protein in typhoid bacteria might keep infected animals alive and provide a safe haven for the microbes.

Read more: Typhoid toxin aids survival in mice

Honorary professor invited to join the European Molecular Biology Organization

An Honorary professor from the Institute of Cancer Sciences has been elected as a member of the European Molecular Biology Organization (EMBO) for 2015.

Read more: Honorary professor invited to join the European Molecular Biology Organization

CMB/LICR Seminar Vassilis Gorgoulis

2015-11-05n - 12:00 to 13:00 Samuelsson, Tomtebodavägen 6Campus Solna

Prof. Vassilis Gorgoulis

Laboratory of Histology-Embryology, Molecular Carcinogenesis Group, Medical School National and Kapodistrian University of Athens, Greece

Title: The Role of the DNA Damage Response Pathway (DDR) in Cancer. Beneficial and Adverse Effects

Host: Teresa Frisan

ARISTEIA II

“Transcriptional reprogramming features triggered by oncogenic Cdc6” Funded by the GSRT with 200.000 Euros, “ARISTEIA II” program, project code 3020, 2014-2015

Cdc6 is a pivotal replication licensing factor. Together with the origin recognition complex (ORC) and Cdt1 they facilitate the loading of the minichromosome maintenance proteins 2-7 (MCM) on the chromatin forming the pre-Replication Complex (pre-RC). Pre-RCs bound to the replication origins, license them to fire once per cell cycle in normal cells. We and others have shown that deranged expression of Cdc6 and Cdt1 leads to re-replication, replication stress and aberrant recombination, which drive genomic instability and promote malignant behavior.

Read more: ARISTEIA II

GSRT Supporting Postdoctoral Researchers grant 2010

Dr. Thodoris Petrakis and the Lab of Histology-Embryology, Medical School of Athens, directed by Professor Vassilis Gorgoulis, applied for the GSRT Supporting Postdoctoral Researchers grant in 2010. The application was approved and the Postdoctoral fellow started in the Lab of Histology-Embryology in March 2011.

Read more: GSRT Supporting Postdoctoral Researchers grant 2010

3rd Infla-Care Annual Meeting

3rd Infla-Care Annual Meeting, 10-11 October 2011, Hotel Aquamarina, Attica, Greece

EMBO Workshop 2011

EMBO Workshop 2011 on “Chromosome structure, damage & repair” (http://events.embo.org/11-chromosome-integrity/)

First Announcement - INsPiRE International Workshop on: Oncogenic Pathways and Antitumor Responses

The University of Athens Cancer Research Group has the pleasure to invite you to the International Workshop on:  Oncogenic Pathways and Antitumor Responses, which will be held in Athens, Greece on April 23-25, 2014.

Read more: First Announcement - INsPiRE International Workshop on: Oncogenic Pathways and Antitumor Responses

INsPiRE

INSPIRE

INtegrating the emerging research Potential of the University of Athens Cancer Research Group in the European research area

Read more: INsPiRE

Regulation of tumor development by p38 MAP kinases

On May 6th, 2011, Prof Angel R. Nebreda from the ICREA, Signalling and Cell Cycle Laboratory, Institute of Research and Biomedicine, Barcelona was hosted at the Lab of Histology-Embryology, Medical School, University of Athens and presented a talk entitled “Regulation of tumor development by p38 MAP kinases”

Ku80 is required for the activation of replication origins and G1/S phase transition and is involved in breast cancer

On May 25th, 2012, Prof Maria Zannis-Hadjopoulos from the Department of Biochemistry, Rosalind and Morris Goodman Cancer Centre,  McGill University, Toronto, Canada was hosted at the Lab of Histology-Embryology, Medical School, University of Athens.

Read more: Ku80 is required for the activation of replication origins and G1/S phase transition and is...

Replicative stress and chronic DNA damage lead to ARF-dependent senescence in BRCA2-deficient cells

On February 10th, 2012, Prof Madalena Tarsounas from Gray Institute for Radiation Oncology and Biology University of Oxford, UK was hosted at the Lab of Histology-Embryology, Medical School, University of Athens and presented a talk entitled "Replicative stress and chronic DNA damage lead to ARF-dependent senescence in BRCA2-deficient cells".

VG New

Prof. Vassilis G. Gorgoulis

Laboratory of Histology-Embryology
Molecular Carcinogenesis Group
Medical School
National and Kapodistrian University of Athens

 

Biomedical Research Foundation of the Academy of Athens

 

Faculty Institute for Cancer Sciences, University of Manchester,
Manchester Academic Health Science Centre, Manchester, UK

Manchester Centre for Cellular Metabolism,
University of Manchester, Manchester Academic Health Science Centre, Manchester

 

EMBO member

 

SenTraGorΤΜ

 

 

 

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